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GHRP-4, or growth hormone releasing peptide 4, is a synthetic drug that causes the body to release natural growth hormones. It works by binding with receptors in the human brain and triggering a chain reaction of events that affect many other organs including the liver, kidneys and muscles. It is used as an injectable formulation for treatment of conditions such as severe burns and chronic infections where there is insufficient healing response from normal levels of GH secretion. This supplement may also be used to enhance athletic performance or muscle mass among those who do not already have enough naturally occurring within their bodies. If you want to know more about this peptide, keep reading!
What exactly is GHRP-4?
GHRP-4 is a peptide consisting of four amino acids. It belongs to the group of growth hormone releasing peptides (GHRPs) which trigger the pituitary gland to produce Human Growth Hormone. GHRP-4 has high selectivity for GH release and has no affinity towards other hormones such as prolactin, cortisol or thyrotropin.
How does it work?
GHRP-4 binds with receptors in the human brain and stimulates them to secrete growth hormone releasing factors (GRFs). GRFs are proteins that stimulate the pituitary gland to produce more growth hormone. This process stimulates cell reproduction, causing muscles, bones and organs to grow faster than they would naturally; however, it can also lead to an increased chance of injury. Also, substances which increase cell reproduction may cause cancerous growths.
Advantages of using growth hormone
Gain lean muscle mass– GHRP-4 is mainly taken by bodybuilders and athletes to build lean muscle mass. It can also help in increase in strength and physical performance for people who already have a well- built body.
Gain weight or treat diseases that decrease muscle mass – GHRP-4 may be prescribed to patients suffering from AIDS, cancer, burns and other illnesses which result in muscular atrophy (wasting away of muscles).
Increase exercise capacity – GHRP-4 supplements may be given to patients suffering from chronic heart failure as it increases their exercise capacity. For this purpose, the drug must be used under strict medical supervision because it has potential side effects such as nausea, fatigue, insomnia etc.Treatment of obesity – This peptide can also be used to treat obesity, but it is mostly prescribed to patients suffering from diabetes. It helps in the utilization of glucose (sugar) and increase insulin sensitivity by acting on the liver, muscles and adipose tissues.
What are the side effects of GH?

GHRP-4 may affect the following organs:
- Liver – taking this drug regularly can increase liver enzymes which cause inflammation, jaundice and even liver cancer.
- Kidneys – it also leads to failure of kidneys because it unloads excess protein through urine. This can be counteracted by drinking lots of water while supplementing with GHRP-4.
- Muscles – if you already have muscle mass, then you should not expect any gains in weight or strength by using this peptide. With prolonged usage, it might lead to muscle tears and injuries due to overworking your muscles during workouts.
- Heart – It affects heart function as it is a peptide that increases blood sugar levels.
What is the recommended dosage?
The standard dosage of GHRP-4 is 2mcg to 10mcg per injection, but for fat loss purposes it is 5mcg to 20mcg per injection. Higher doses are also used by some bodybuilders which range from 10 mcg to 30 mcg, but it can cause side effects such as nausea, headaches and vomiting. It may be injected subcutaneously or intramuscularly at least 45 minutes before exercise because it takes time for it to get into your system. If you are taking this supplement alongside proper dieting and exercises, then the results will be visible within 3 months. It should not be taken for more than 6 months at a time. This peptide is not meant for long term use because it causes muscle growth and also gives rise to the production of IGF-1, which can cause cancer if used in high doses for too long.
GHRP-4 advantages over other GH secretagogues:
- It has no effect on cortisol levels – When taken with anabolic steroids, cortisol levels may increase due to increased protein breakdown. GHRP-4 does not affect these levels and thus cannot be detected by anti-doping tests such as the SAM (systolic arterial blood pressure) test used by Olympic committees.
- It maintains normal libido– Although this drug boosts testosterone production at least temporarily during injection period, it does not cause any changes in LH or FSH levels.
- It is non-toxic – No dose limiting toxicity has been observed with use of this drug, even when used at doses higher than 100mcg per day for 3 months.
- It doesn’t cause water retention– This peptide does not result in fluid retention because it has no effect on cortisol and aldosterone production which are involved in the reuptake of sodium ions into extracellular fluids resulting in swelling.
Who can benefit from HGH?
GHRP-4 can be used by both men and women for increasing GH levels. It is also beneficial in the following cases:
- It increases growth hormone levels – GHRP-4 is a powerful GH secretagogue which stimulates the anterior pituitary gland to secrete more GH into the blood stream. This peptide has been studied mostly in adults, but it has been observed that it can increase GH secretion even in children with growth disorders such as Prader Willi syndrome (increased appetite, obesity and shortness of height). However, it should not be given to pregnant women because it may cause developmental defects in their fetuses.
- Lowers body fat – The best thing about taking GHRP-4 or other similar compounds with similar effects is that they cause fat loss without any exercise or dieting. However, it should not be used for prolonged periods because it causes muscle growth and low testosterone levels as well as high cortisol levels which result in abdominal obesity and water retention.
- Increases energy – People who use GHRP-4 report an increase in their energy levels as a result of the improved function of internal organs such as liver and kidneys which results from enhanced protein breakdown. Also, this peptide inhibits serotonin production, so you feel more energetic with an improved mood and mental alertness.
- Increases appetite – Users report increased hunger after taking this drug which is beneficial for people suffering from underweight conditions such as eating disorders and malnutrition due to chronic diseases like cancer etc.
- Combats aging – This peptide is also said to slow down the process of muscle loss and osteoporosis in elderly people. However, more studies are required to prove its efficacy in this regard.
- Lowers blood pressure – GHRP-4 can cause a noticeable decrease in systolic blood pressure by around 10mmHg within 2 hours of administration. People who have low blood pressure may experience dizziness after taking it.
- Increases lean body mass – Since GH increases IGF-1 levels which causes muscle growth, taking GHRP-4 can help you get ripped much quicker than normal if combined with proper dieting and exercise regimen.
- Improves skin health – Skin elasticity is maintained while collagen synthesis increases upon injection of GHRP-4 resulting in improved moisture and texture of the skin.
Are any other compounds similar to growth hormone?

There are several compounds which have been developed from GHRH’s, but they can no longer be legally manufactured since they were scheduled as controlled substances by the DEA. However, there are still some “research chemicals” from various companies that come close enough to these illegal chemicals that they should give similar results when used for increasing GH levels like GHRP-4. Scientists are still developing newer compounds for increasing GH secretion but until they get approved for medical use, you can consider these following products legal alternatives to GHRP-2:
- Ipamorelin – This peptide is said to be 100 times more potent than GHRH’s which means that its effects will be noticed after very small doses (0.01mg/kg).
- CJC1295 (DAC) – It has been observed that DAC converts into CJC 1295 when ingested orally, so it should have similar effects as described above.
Melanotan II – This compound is used by bodybuilders and other athletes in tanning competitions because of its ability to darken skin color by increasing melanin (pigment) production in the body. However, its side effects like low libido and erectile dysfunction may make it less appealing to people who wish to increase their GH levels naturally.
Is GHRP-4 effective?
Yes, this peptide is very effective when combined with GHRH’s (Sermorelin, Modified GRF 1-29 etc.) or other similar compounds like CJC 1295 (DAC). It results in increased GH secretion which leads to improved protein synthesis and breakdown ultimately giving users an “enhanced” look. People who use GHRP-4 report an increase in their energy levels as well as strength since the peptide causes better blood circulation into your muscles which provides them with more oxygen and nutrients for improved growth.
How does GH help in fat loss?
GHRP-4 inhibits serotonin production, so you feel more energetic with an improved mood and mental alertness. This means that it will be easier for you to exercise regularly while following a low-calorie diet plan since your energy levels won’t drop drastically like they do when on other weight loss drugs/supplements which elevate the production of serotonin (a molecule responsible for sedation). Also, this peptide increases appetite which might make it difficult for people to control their food intake by having small portions of food at regular intervals throughout the day. However, exercising regularly combined with increased dietary protein intake can offset this effect to some extent.
Product reviews for GHRP-4:
- David Nathaniel (June 1, 2021): I have been using GHRP-4 from for the last 3 months and I must say that it works great! I started feeling changes in about a week’s time which increased my appetite, improved my mood and made me much stronger. My friends who trained with me were surprised at how easily I was able to lift more weight than them even though we had similar body types.
- Kurt Fenson (September 30, 2021): GHRP-4 helps in muscle gain without any significant side effects or insulin spikes if taken for a short period of time when combined with other supplements like DHEA, Testosterone Booster etc. However, if you plan to use it longer term then you may experience low blood sugar levels and insulin resistance which can be avoided if you use GHRH’s like Sermorelin.
- Shawn Stacy (October 1, 2021): I first started using this peptide for getting rid of wrinkles and I was really surprised with the results. It actually decreased my wrinkles and made me look 2 years younger within a few weeks! So now I have been taking it regularly to maintain my skin health as well as energy levels.
- Armando Manalo (October 2, 2021): First of all, GHRP-4 is legal in my country and it’s really helpful in cutting cycles due to its appetite increasing effects. It decreases the water retention by stimulating glucocorticoid receptors which means that you can consume more carbs without gaining much weight. Also, I was able to lose weight effortlessly since I had a very high metabolic rate because of this peptide so I didn’t even have to exercise regularly.
- Steve Strickland (October 3, 2021): The best thing about GHRP-4 is that it doesn’t have any side effects since it’s a synthetic peptide hormone which means that it increases GH to normal levels only throughout the duration of intake unlike other similar products like CJC 1295 DAC where you need to inject yourself regularly with large dosages for months to get good results. On top of that, it doesn’t harm your immune system because there are no foreign molecules present in this supplement unlike HGH injections.
- Jamie Smith (October 5, 2021): This peptide has done nothing for me except making my fat deposits more visible. There’s really tightness in my skin which I don’t like at all especially because it’s a permanent thing. Since the day I started using this peptide, muscle definition has gone down, and my strength is decreasing gradually with time.
- Dylan Owen (October 7, 2021): It seems that GHRP-4 is a good product for those who have been working out regularly but still not getting the results they desire. But as far as beginners are concerned, it’s better to take some basic supplements first so that you can build your body from the inside by increasing natural HGH production before taking products like GHRP-4 which will give you only temporary benefits!
- Claire Jameson (October 9, 2021): If there is one peptide product also known as ghrelin mimetic then it must be GHRP-4 as it is far more powerful than any other such product out there in the market currently. It decreases my appetite and gives me energy throughout the day without making me feel tired or worn down like most other products do at times. This formulated peptide has really helped me cut down weight in a very short time period so I would suggest it to anyone who wants to achieve their fitness goals the natural way!
- Thomas Cyrus (October 11, 2021): After using GHRP-4 for about 5 months, I found that it was not only effective in stimulating the release of human growth hormone but also very safe to use as compared to other ghrelin mimetics. One thing that stood out about this peptide product is that I didn’t have a problem with its dosage because it is relatively milder than other products which means you can easily adjust the dose according to your needs and requirements without feeling too much hunger or fatigue.
- Maxim Brown (October 13, 2021): Since I am a bodybuilder, my trainer advised me these products so as to gain faster muscles and leaner physique within a shorter period of time. He suggested me GHRP-4 along with GHRP-2 to double the benefits for faster results. I used it as per his instructions and now I have started noticing a lot of changes in my body. My muscles are much leaner, well-shaped and harder than before so I think this peptide is pretty effective after all!
- Lily Willson (October 15, 2021): In terms of price, you cannot find a better ghrelin mimetic peptide product than GHRP-4 because there are no side effects which means this product has been made from 100% natural ingredients only unlike other such products that contain foreign molecules which will be harmful for your health eventually.
- Davin Mac (October 21, 2021): Anyone who comes across this peptide drug must realize that it works differently than other ghrelin mimetics because it not only stimulates the release of growth hormone, but also modulates its own amount, allowing your body to create enough HGH even without taking injections or medications. As a result, if you want long-term benefits, I highly recommend you start with GHRP-4. It’s really helped me!
- Karlos Juan (October 23, 2021): If you are looking for a milder peptide drug which will help your body to stimulate the release of growth hormone naturally, then GHRP-4 might be the product for you. I’ve used it and found that even though this product is not as powerful as some other ghrelin mimetics on the market, its effects are quite long-lasting. I have been using it for the last 3 months and it has helped me in my workouts by stimulating protein synthesis which is a great thing if you want to build muscles fast!
- Jodie Jacob (October 25, 2021): In terms of safety and effectiveness, GHRP-4 can be used without any doubt when compared to any other ghrelin mimetic drug out there. I have been using this product for the last 3 months and found that it relieves me from my hunger cravings by suppressing my desire of food without making me feel too tired unlike other products which will make you feel lethargic in a few days of using them.
- Anna Malone (October 29, 2021): I was really fed up with the low energy levels and tiredness which stopped me from achieving my fitness goals until I discovered GHRP-4. This is an effective ghrelin mimetic peptide drug that has helped me cut down my weight in a very short period of time. Although I am going to continue taking this product for some more time, I have already started noticing the positive changes in my body.
FAQ’s about GHRP-4:
What is the most important information I should know about this peptide?
This peptide has been shown to increase your body’s natural production of HGH and it doesn’t come with any side effects as well. So, why would you want to buy other unapproved human growth hormone products?
What kind of benefits can I expect from GHRP-4? Is it really effective?
You will experience lean muscle gains within a very short period of time without experiencing any bad effects or adverse reactions.
How should I take GHRP-4 exactly so that I get better results out of it?
No matter how much you eat, GHRP-4 will reduce your appetite and make you feel more energetic. Just follow the instructions given on the product label or consult a physician before using this peptide drug.
How long will it take to see results?
GHRP-4 has been known to start working within one month of continued use and it does not cause any adverse effects either!
What kind of precautions should I keep in mind while using this peptide drug?
Do not exceed the recommended dosage because it can have some serious side effects if used for too long, so please stick to 2 injections per day or under its supervision.
IS GHRP-4 legal?
Yes, it is 100% legal because this peptide drug does not contain any type of human-made hormones like steroids do.
Do I need a prescription to buy GHRP-4?
No prescription required because this product has been made from natural ingredients only which means you can buy it without a doctor’s consultation as well!
With GHRP-4, you may get a leaner, stronger, and healthier body!

A peptide drug like GHRP-4 is what you should go for if you are looking to make your body more lean, strong and healthy. So, stop wasting your money on other products that won’t work for you, or worse, end up harming your health eventually! Go for the safest growth hormone releaser available in the market today – GHRP-4 – which will help you achieve long results safely and quickly!